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According to the Mayo Clinic, some of these possible interactions include: Substrates for cytochrome P450 2C9, such as Valium (diazepam) and Jantoven (warfarin) Some diabetes medications Evista (raloxifene) Olysio (simeprevir) Rapamune (sirolimus) Other medications, such as those that treat allergies, high cholesterol, anxiety, and cancer, could also interact with milk thistle, according to Mount Sinai

GLP-1 medications are not FDA-approved for Type 1 diabetes

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It means the user has moved into a different phase of the treatment pathway

Trying a different version of the new class of drugs may help